Last update
5/2/2025
Research Authors

Overview

SCIENTIFIC SCORE
Questionable
Based on 5 Researches
6.6
USERS' SCORE
Moderately Good
Based on 13 Reviews
7.6
Supplement Facts
Serving Size: 2 Tablets
Amount Per Serving
%DV
Calcium (elemental) (from 2,775 mg complex of Calcium Carbonate, Calcium Citrate, Calcium Ascorbate)
1 g (1,000 mg)
77%
Magnesium (elemental) (from 928 mg complex of Magnesium Oxide, Magnesium Citrate, Magnesium Ascorbate)
500 mg
119%

Top Medical Research Studies

8
Magnesium potentially benefits CFS patients
We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.

In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.

In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
Read More
7
Magnesium sulfate shows potential benefits
We aimed to understand the effects of magnesium sulfate treatment on a patient with chronic fatigue syndrome. The case involved a 29-year-old woman experiencing severe fatigue alongside various symptoms, including swelling lymph nodes and muscle pain.

After other treatments failed to provide relief, we administered magnesium sulfate intravenously once a week. Remarkably, after six weeks, the patient reported a significant reduction in fatigue and improved daily functioning, eventually leading to her discharge from the hospital.
Read More
7
Magnesium shows limited benefit for fatigue
We investigated how magnesium levels relate to chronic fatigue by studying 93 patients with unexplained fatigue.

Around 47% of participants showed magnesium deficiency, linked to reduced plasma antioxidant capacity.

Although magnesium supplementation didn't increase blood glutathione levels, we observed improved magnesium stores and vitamin E levels.

However, this did not equate to a significant boost in antioxidant activity or a decrease in lipid vulnerability. Therefore, while magnesium may help improve some parameters, it is not a panacea for chronic fatigue syndrome.
Read More

Most Useful Reviews

9
Helpful but large
1 people found this helpful
I have used this product repeatedly as I suffered from chronic constipation and required magnesium. I usually consume seaweed like wakame and hijiki, but I also take supplements. However, these tablets are rather large and occasionally get stuck in my throat, perhaps due to their size and my age. It would be beneficial if they could be made smaller and allow for the intake of two tablets at a time.
Read More
9
Helpful but large
1 people found this helpful
I have used this product repeatedly as I suffered from chronic constipation and required magnesium. I usually consume seaweed like wakame and hijiki, but I also take supplements. However, these tablets are rather large and occasionally get stuck in my throat, perhaps due to their size and my age. It would be beneficial if they could be made smaller and allow for the intake of two tablets at a time.
Read More
9
Important magnesium source
1 people found this helpful
I have repeatedly purchased this product due to my chronic constipation and need for magnesium. I typically consume seaweed varieties like wakame and hijiki, but I also rely on supplements. However, they're rather large, and I occasionally struggle to swallow them, possibly due to their size. It would be beneficial if the tablets were smaller and I could take two instead.
Read More

Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 5 Researches
6.6
  • All Researches
8
Magnesium potentially benefits CFS patients
We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.

In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.

In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
Read More
7
Magnesium shows limited benefit for fatigue
We investigated how magnesium levels relate to chronic fatigue by studying 93 patients with unexplained fatigue.

Around 47% of participants showed magnesium deficiency, linked to reduced plasma antioxidant capacity.

Although magnesium supplementation didn't increase blood glutathione levels, we observed improved magnesium stores and vitamin E levels.

However, this did not equate to a significant boost in antioxidant activity or a decrease in lipid vulnerability. Therefore, while magnesium may help improve some parameters, it is not a panacea for chronic fatigue syndrome.
Read More
7
Magnesium sulfate shows potential benefits
We aimed to understand the effects of magnesium sulfate treatment on a patient with chronic fatigue syndrome. The case involved a 29-year-old woman experiencing severe fatigue alongside various symptoms, including swelling lymph nodes and muscle pain.

After other treatments failed to provide relief, we administered magnesium sulfate intravenously once a week. Remarkably, after six weeks, the patient reported a significant reduction in fatigue and improved daily functioning, eventually leading to her discharge from the hospital.
Read More
7
Magnesium shows promise for CFS
We explored the effects of magnesium on chronic fatigue syndrome (CFS), a condition marked by extended periods of debilitating fatigue. While there’s no definitive therapy established for CFS, our review of clinical trials reveals that magnesium treatment has shown promise, enhancing the well-being of some patients.

Other treatments like acyclovir have proven ineffective, and although intravenous immunoglobulin therapy shows potential, its results remain debated. We recognize that restoring immune function may be a piece of the puzzle, but overall, the effectiveness of magnesium for treating CFS symptoms is yet to be firmly established.
Read More
4
Limited magnesium effectiveness in CFS
We systematically reviewed randomized controlled trials on complementary and alternative medicine (CAM) treatments for chronic fatigue syndrome (CFS).

Although 26 studies involving over 3,000 participants explored various therapies, the findings showed limited effectiveness overall.

While some treatments like massage and specific dietary supplements had some positive effects, most failed to provide significant benefits.

Notably, magnesium showed potential, but due to small sample sizes and biases in the studies, we can't make firm conclusions just yet. More rigorous studies are needed to confirm these effects.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 13 Reviews
7.6
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Helpful but large
1 people found this helpful
I have used this product repeatedly as I suffered from chronic constipation and required magnesium. I usually consume seaweed like wakame and hijiki, but I also take supplements. However, these tablets are rather large and occasionally get stuck in my throat, perhaps due to their size and my age. It would be beneficial if they could be made smaller and allow for the intake of two tablets at a time.
Read More
9
Helpful but large
1 people found this helpful
I have used this product repeatedly as I suffered from chronic constipation and required magnesium. I usually consume seaweed like wakame and hijiki, but I also take supplements. However, these tablets are rather large and occasionally get stuck in my throat, perhaps due to their size and my age. It would be beneficial if they could be made smaller and allow for the intake of two tablets at a time.
Read More
9
Important magnesium source
1 people found this helpful
I have repeatedly purchased this product due to my chronic constipation and need for magnesium. I typically consume seaweed varieties like wakame and hijiki, but I also rely on supplements. However, they're rather large, and I occasionally struggle to swallow them, possibly due to their size. It would be beneficial if the tablets were smaller and I could take two instead.
Read More
7.5
Consumption concerns
1 people found this helpful
This is a regularly purchased product for my chronic constipation and magnesium intake. I typically consume seaweeds such as wakame and hijiki but also rely on these tablets. The size can be a challenge as sometimes they get stuck in my throat, possibly due to my age. A slightly smaller tablet would indeed be welcome.
Read More
9
Helpful but large
I have used this product repeatedly as I suffered from chronic constipation and required magnesium. I usually consume seaweed like wakame and hijiki, but I also take supplements. However, these tablets are rather large and occasionally get stuck in my throat, perhaps due to their size and my age. It would be beneficial if they could be made smaller and allow for the intake of two tablets at a time.
Read More

Frequently Asked Questions

6
Improved mood
I had low vitamin D levels and suffered from hair loss, chronic fatigue syndrome, and irritability. I began taking 5000 units of vitamin D3 alongside Omega-3 and calcium with magnesium. After a month, my hair loss decreased, it became easier to wake in the morning, and my mood stabilised. I take these vitamins at night in pairs. Despite current family stresses, these vitamins have helped me feel calmer. I appreciate the manufacturer for their effect.
9
Helpful but large
1 people found this helpful
I have used this product repeatedly as I suffered from chronic constipation and required magnesium. I usually consume seaweed like wakame and hijiki, but I also take supplements. However, these tablets are rather large and occasionally get stuck in my throat, perhaps due to their size and my age. It would be beneficial if they could be made smaller and allow for the intake of two tablets at a time.
4
Limited magnesium effectiveness in CFS
We systematically reviewed randomized controlled trials on complementary and alternative medicine (CAM) treatments for chronic fatigue syndrome (CFS).

Although 26 studies involving over 3,000 participants explored various therapies, the findings showed limited effectiveness overall.

While some treatments like massage and specific dietary supplements had some positive effects, most failed to provide significant benefits.

Notably, magnesium showed potential, but due to small sample sizes and biases in the studies, we can't make firm conclusions just yet. More rigorous studies are needed to confirm these effects.
8
Magnesium potentially benefits CFS patients
We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.

In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.

In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
7
Magnesium shows promise for CFS
We explored the effects of magnesium on chronic fatigue syndrome (CFS), a condition marked by extended periods of debilitating fatigue. While there’s no definitive therapy established for CFS, our review of clinical trials reveals that magnesium treatment has shown promise, enhancing the well-being of some patients.

Other treatments like acyclovir have proven ineffective, and although intravenous immunoglobulin therapy shows potential, its results remain debated. We recognize that restoring immune function may be a piece of the puzzle, but overall, the effectiveness of magnesium for treating CFS symptoms is yet to be firmly established.

References

  1. Alraek T, Lee MS, Choi TY, Cao H, Liu J. Complementary and alternative medicine for patients with chronic fatigue syndrome: a systematic review. BMC Complement Altern Med. 2011;11:87. 10.1186/1472-6882-11-87
  2. Manuel y Keenoy B, Moorkens G, Vertommen J, Noe M, Nève J, et al. Magnesium status and parameters of the oxidant-antioxidant balance in patients with chronic fatigue: effects of supplementation with magnesium. J Am Coll Nutr. 2000;19:374.
  3. Takahashi H, Imai K, Katanuma A, Sugaya T, Hisano K, et al. [A case of chronic fatigue syndrome who showed a beneficial effect by intravenous administration of magnesium sulphate]. Arerugi. 1992;41:1605.
  4. Uchida A. [Therapy of chronic fatigue syndrome]. Nihon Rinsho. 1992;50:2679.
  5. Cox IM, Campbell MJ, Dowson D. Red blood cell magnesium and chronic fatigue syndrome. Lancet. 1991;337:757.
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